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StripAssays |
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ViennaLab Platform is based on sequence specific hybridisation following amplification by PCR. New tests are developed continuously, in parallel of the existing kits.
StripAssays are for multi-mutation assays, and used as macro-arrays for the genotyping of mutations linked to a particular genetic diseases.
Each StripAssay kit provides all the reagents necessary to perform 20 tests in parallel. The entire assay can be accomplished in less than 6 hours without costly equipment. All kits include ready-to use reagents for the isolation of DNA from human whole blood, the in vitro amplification of targeted gene sequences, and the subsequent detection of mutations by reverse hybridisation.
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The procedure includes three steps :
DNA is isolated from anticoagulated blood by a rapid and convenient procedure. Then, gene sequences are simultaneously in vitro amplified and biotin-labelled in a single (“multiplex”) amplification reaction. Finally, the amplification products are selectively hybridised to a test strip, which contains oligonucleotide probes (wild type- and mutant- specific) immobilized as parallel lines. Bound biotinylated sequences are detected using streptavidin-alkaline phosphatase and color substrates.
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| StripAssays are CE-marked and validated for the in vitro diagnostics. |
NEW FOR BETA-THALASSEMIA !
BETA-GLOBIN STRIPASSAYS :
ViennaLab offers reliable and convenient reverse-hybridisation assays tailored to population-specific mutations in the Mediterranean region (MED), the Middle East and India (IME) and Southeast Asia (SEA).
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> beta-Globin StripAssay MED: 22 mutations covering >90% of b-globin defects found in Mediterranean countries
> beta-Globin StripAssay IME: 22 mutations covering >90% of b-globin defects found in the Middle East and India
> beta-Globin StripAssay SEA: 22 mutations covering >90% of b-globin defects found in Southeast Asia
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Download the file
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| Reference |
StripAssay |
Description |
PDF |
V4-160 |
Alpha-Globin StripAssay for alpha- Thalassemia |
21 mutations
(2 strips) |
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V4-120 |
ß-Globin StripAssay for beta- Thalassemia |
22 mutations |
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NEW ! V4-130 |
ß-Globin MED StripAssay |
22 mutations |
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NEW ! V4-140 |
ß-Globine IME StripAssay |
22 mutations |
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NEW ! V4-150 |
ß-Globine SEA StripAssay |
22 mutations |
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V4-230 |
Familial Mediterranean Fever (FMF) StripAssay |
Detection of 12 MEFV gene mutations |
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V4-210 |
Haemochromatosis StripAssay B |
Detection of 3 HFE gene mutations: C282Y, H63D, S65C |
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V4-200 |
Haemochromatosis StripAssay D |
12 mutations
HFE, TFR2, FPN1 genes |
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V4-220 |
Haemochromatosis StripAssay A |
Detection of 18 mutations: twelve HFE mutations, four TFR2 mutations and two FPN1 mutation |
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V4-240 |
CVD StripAssay |
Testing for 12 mutations / polymorphisms associated with cardiovascular disease |
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V4-260 |
FV+PTH+MTHFR StripAssay |
Detection of the Factor V Leiden, Prothrombin and MTHFR gene mutations |
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V4-290 |
FV+PTH StripAssay |
Detection of the Factor V Leiden and Prothrombin gene mutations |
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V4-280 |
APO E StripAssay |
Determination of isoforms apo E2, E3 and E4 |
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V4-250 |
Gaucher Disease StripAssay |
Detection of 8 glucocerebrosidase (GBA) gene mutations and two recombinant alleles |
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V4-310 |
Sugar Intolerance StripAssay |
Detection of two lactase-phlorizin hydrolase (LPH) gene mutations and four aldolase B gene mutations |
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V4-710 |
PGX-HIV StripAssay |
MDR1, CYP2D6, CCR5 genes |
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V4-720 |
PGX-5FU StripAssay |
DPYD mutation |
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StripAssay Evaluator Software |
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Version 2.0 of Evaluator now available !
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Software for automated strip scanning and interpretation of results.
In combination with an off-the-shelf scanner, the Evaluator software permits one-step, automated analysis of up to 20 strips. The software converts the colour intensity of the StripAssay bands into digital data that can be stored electronically. The software allows precise and effortless analysis of complex StripAssays.
Download the PDF file
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> Easy Handling : Test type and lot number are automatically recognized via bar codes
> Easy Interpretation : Results are automatically analysed and displayed in comprehensive form
> Easy Safe-Guard : Unusual results trigger an in-built warning system
> Easy Data Storage : Test results can be archived, exported and cross-referenced
> Minimal Configuration : Windows 2000 or XP, 256 MB RAM
Compatible with all the existing StripAssays available
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| Contact us for a demo ! |
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Materials and Accessories |
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| Reference |
Product |
Format |
V4-160-AM |
Alpha-Globin amplification buffer |
3 x 250 µl |
V4-120-AM |
ß-Globine amplification buffer |
20 tests |
V4-130-AM |
ß-Globin amplification buffer (MED, IME, SEA series) |
20 tests |
V4-210-AM |
StripAssay B Haemochromatosis amplification buffer |
20 tests |
V4-200-AM |
StripAssay D Haemochromatosis amplification buffer |
20 tests |
V4-220-AM |
StripAssay A Haemochromatosis amplification buffer |
20 tests |
V4-230-AM |
StripAssay FMF amplification buffer |
20 tests |
V4-240-AM |
StripAssay CVD amplification buffer |
20 tests |
V4-250-AM |
StripAssay Gaucher Disease amplification buffer |
20 tests |
V4-260-AM |
StripAssay FV+PTH+MTHFR amplification buffer |
20 tests |
V4-280-AM |
StripAssay Apo E amplification buffer |
20 tests |
V4-290-AM |
StripAssay FV+PTH amplification buffer |
20 tests |
V4-710-AM |
StripAssay PGX-HIV amplification buffer |
20 tests |
V4-720-AM |
StripAssay PGX-5FU amplification buffer |
20 tests |
VCS-012 |
StripAssay Detection Reagents |
20 reactions |
V2-014 |
GEN-X-TRACT kit
download the file |
100 extractions |
V2-020 |
Spin Micro DNA Extraction System
For genomic DNA extraction, simple and quick (total blood, blood spotted onto membrane, cells pellet, amniotic fluid, tissues)
download the file |
20 extractions |
V6-080 |
Racks for genotyping |
5 units |
V-TR10 |
Racks for ProfiBlot T48 (Auto-LiPA Innogenetics)
Specially designed for a routine use on automate station |
10 units |
V-TP05A |
Super Taq ADN Polymerase - 500 u
to optimise PCR reactions (recommended for Alpha-Globin StripAssay) |
1 tube |
V-TP05B |
Super Taq ADN Polymerase - 1000 u |
1 tube |
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